An electrochemical sensor based on [Ru(bpy)2dpp]2+/SMWCNTs/Au modified glassy carbon electrode for the detection of 5?-GMP

Abstract A sensitive electrochemical sensor for the selective detection of 5?-guanylic acid (5?-GMP) was prepared by combining sulfonated-multiwalled carbon nanotubes (SMWCNTs) and [Ru(bpy) 2 dpp]Cl , which were dripped on surface a glass electrode (GCE) immobilized with gold nanoparticles. The 5?-GMP biosensor fabricated using dpp] 2+ /SMWCNTs/Au/GCE as working, Ag/AgCl reference Pt auxiliary connected an workstation. modified characterized cyclic voltammetry (CV) impedance spectroscopy (EIS). results showed sensor’s response current had best peak shape maximum when pH electrolyte 3, scan speed CV in range 100 to 180 mV/s, enrichment time 200 300 s. Under optimum conditions, linear analytical curve obtained concentrations 0.01 0.5 mmol L ?1 limit 0.0014 . exhibited good consistent data from liquid chromatography. has reproducibility, long-term stability strong immunity interference, may be powerful device detection, great advantages such simple preparation operation, low equipment cost.